Manchester City will assess the fitness of Bernardo Silva, Ilkay Gündogan and Gabriel Jesus before the visit of Bournemouth.
All three of the regular starters missed Tuesday’s 2-2 draw in Lyon on Tuesday evening.
Benjamin Mendy, Claudio Bravo and Kevin de Bruyne also remain sidelined.
One man who is fit, and most certainly firing this season, is Raheem Sterling. The winger scored once and assisted twice in the demolition of West Ham United at the London Stadium last weekend and has scored in all five of his Premier League games against Bournemouth, netting seven in total.
The England international has the opportunity to become the first player in Premier League history to score in his first six appearances against a particular club.
As for the away side, Dan Gosling is unlikely to feature after injuring his knee against last time out, although the problem is not thought to be serious or long-term.
Summer signing Jefferson Lerma, who scored a remarkable own-goal in the 2-1 defeat to Arsenal last Sunday, is suspended after already picking five yellow cards.
Bournemouth have lost three games on the bounce, all by a 2-1 scoreline, and the Etihad Stadium is probably the worst place to visit when trying to turn your form around.
However, Bournemouth have beaten reigning Premier League champions three times in six games since promotion to the top flight in 2015. Only City, with five wins, have a better record in this period.
Despite the impressive record, though, Manchester City have won the six previous league encounters between the two sides; scoring 21 times and conceding just twice.
In fact, Bournemouth have never beaten the Cityzens in a competitive fixture (D2, L10).
Compounding this fact, The Cherries have conceded 13 times in their three previous trips to the Etihad Stadium, losing 5-1 on their first visit in 2015 and 4-0 in the subsequent matches in 2016 and 2017.
City are unbeaten in their last 19 league games (W16, D3), conceding just eight goals in the remarkable run. They are also undefeated in their last 35 league matches which have kicked off at 3pm on a Saturday, winning 31, which is rather unsurprisingly a Premier League record.
City are also yet to concede in the final half hour of a league match this season and are the only club who have not thrown any points away from winning positions.
Considering that Bournemouth have lost their last six games against established top-six opposition, I don’t hold out much hope for them in this one.
Their defence is leaking goals right now and, despite the fact that they sit in eighth position in the league table, their last win in such a fixture was the 3-0 victory away to Chelsea in January.
Add to this that all but one of Sergio Agüero’s last 19 Premier League goals have been scored at the Etihad, and Manchester City should be set for another comfortable home win and stay top of the Premier League table. But the champions cannot afford to be complacent.
PREDICTED RESULT: 3-1